A special operations unit called the Rapid Response Tactical Squad is deployed to the Olduvai research station on Mars after communication is lost and a security breach is reported. Led by Sarge, the team enters the facility to find it under a high-level quarantine. They discover that an experiment involving alien DNA has gone wrong, as a test subject has escaped and begun killing the staff. Dr. Grimm, who is related to a team member named Reaper, explains that the alien chromosomes are infectious and capable of mutating humans into violent monsters.
Directed by Andrzej Bartkowiak, this action horror film was released in 2005 and is the fourth project in the director's chronological filmography. The movie stars Dwayne Johnson as Sarge, Karl Urban as Reaper, and Rosamund Pike as Samantha Grimm. It was a co-production between the United States, the United Kingdom, Germany, and the Czech Republic.
The film operated on a 60 million USD budget and earned slightly less than that amount, with 58 million USD in worldwide box office returns. Audience reception is mixed, with a 5.2 rating on IMDb from 123,000 votes and a 5.2 rating on TMDB from 2,533 votes. Professional critics gave the film a lower score of 4.2.
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