Alice Howland is a linguistics professor at Columbia University, married with three grown children and settled into a life she has built around language. She begins to lose words, then to lose her bearings on the streets of Manhattan, and the diagnosis she eventually receives is early-onset Alzheimer's disease, a rare and inherited form. The film follows what the illness does to her and to the people around her, including her husband John and her children Anna, Tom and Lydia, as the family's assumptions about the future give way to something none of them chose.
Richard Glatzer and Wash Westmoreland directed and wrote the screenplay, the second feature they made together after The Fluffer in 2001; Westmoreland went on to direct Colette, Earthquake Bird and Heartstopper Forever. Julianne Moore plays Alice, with Alec Baldwin as John, Kate Bosworth as Anna, Hunter Parrish as Tom and Seth Gilliam among the credited cast.
Made for about 5 million dollars, the film took roughly 45 million worldwide, a strong return on a modest production. On IMDb it holds 7.5 out of 10 from around 150,000 votes, and on TMDB 7.5 from a few thousand, while the critics' rating stands at 7.4 from just over 200 reviews, placing professional and audience response in close agreement.
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